Changes in quality of life associated with complications of diabetes: Results from the ADVANCE study

A Hayes; H Arima; M Woodward; J Chalmers; N Poulter; P Hamet; P Clarke

Journal article

Changes in quality of life associated with complications of diabetes: Results from the ADVANCE study

A Hayes, H Arima, M Woodward, J Chalmers, N Poulter, P Hamet, P Clarke

Value in Health | ELSEVIER SCIENCE INC | Published : 2016

DOI: 10.1016/j.jval.2015.10.010

Abstract

Objective To measure the impact of complications on summary measures of health-related quality of life among people with type 2 diabetes. Methods Patients participating in the Action in Diabetes and Vascular Disease:Preterax and Diamicron MR Controlled Evaluation (ADVANCE) trial were administered a health-related quality-of-life questionnaire, the three-level EuroQol five-dimensional questionnaire (EQ-5D-3L), on four occasions over a 5-year period. We used two-way fixed-effects longitudinal regression models to investigate the impact of incident diabetes complications (stroke, heart failure, myocardial infarction, ischemic heart disease, renal failure, blindness, and amputation) on EQ-5D-3L ..

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University of Melbourne Researchers

Philip Clarke Author

Stephen Harrap Author

Related Projects (1)

USING HEALTH ECONOMICS TO STRENGTHEN TIES BETWEEN EVIDENCE POLICY AND PRACTICE IN CHRONIC DISEASE

There is a major shortage of researchers with health economics expertise in Australia. This grant will provide training and development for ..

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

This study was supported by the National Health and Medical Research Council of Australia (NHMRC) (project grant 571372). The ADVANCE trial (clinical trial reg. no. NCT00145925, clinicaltnals.gov) was partially funded by the NHMRC (project grant ID 211086 and program grants 358395 and 571281) and by Servier International.